The Luxembourg Football Federation manages the Luxembourg national football team, who hosts their matches at Stade Josy Barthel. Despite never reaching the finals of a major tournament, the team, known as Les Lions Rouges, often poses a challenge for European teams during qualifiers.

Luxembourg emerged victorious against Macedonia in the Euro 2016 qualifiers, however their most significant achievement is defeating Czech Republic in the 1996 European Championship qualifying match. The team, also known as Les Lions Rouges, dons red shirts and red shorts for their home games, but switches to white jerseys and white shorts for away matches.

Jeff Strasser is known as the most renowned and experienced player from Luxembourg, having played 98 games for the national team. A noteworthy moment for Luxembourg was their 6-0 victory over Afghanistan in a match held in London in 1948. However, they also faced their biggest defeat at the hands of England, losing 9-0 twice (in 1960 and 1982).